Sublingual products are the preferred treatment for many cancer patients who are taking full extract cannabis oil; frequently attributed to as Rick Simpson Oil, THC Oil or Hemp oil. In the case of direct sublingual administration, precisely decarboxylated cannabis is placed under the tongue so that the cannabinoids immediately enter the bloodstream through the vascular tissues in the sublingual cavity.
Cannabis can also enter the bloodstream before swallowing. Under the tongue and in the mouth, there are a large number of blood vessels that can absorb cannabinoids. Common examples of this type of medication are soluble strips, sublingual sprays or medicinal tablets or tinctures.
Sublingual administration is not only a socially acceptable and convenient form of medication but also a very effective way of taking cannabinoids through the oral mucosa. Due to the increased bioavailability of cannabinoids, this method allows a fast and adequate intake directly into your systemic circulation.
“Ingestion through blood vessels and microcapillaries in the mouth is one of the best ways to increase the bioavailability of cannabinoids.”
Bioavailability is a subset of absorption in pharmacology; it refers to the proportion of an administered dose of an unchanged drug that enters the bloodstream. The only way to achieve 100% actual bioavailability is by definition intravenous administration of a drug.
In comparison to other methods of administration, uptake by blood vessels and microcapillaries in the mouth is probably the most effective way to increase the bioavailability of cannabinoids. This “first pass” of drugs, as it is called, does not require the medication to enter the liver where it would be broken down, making it significantly less useful and bioavailable.
Whenever you take other medications orally, digesting capsules or eating an edible meal; a small portion of this drug is metabolized in the liver before it even reaches the bloodstream, thereby reducing the overall bioavailability of the drug.
Besides, sublingual administration provides rapid smoking-like effects, but without exposing the lungs to heat, tar or other undesirable side effects; including unpleasant smoke odour, smoky taste, dry mouth, throat irritation caused by both smoke and hot embers, which are common enter the lungs mouth and lungs of the user during administration. In inflammation, a large percentage of cannabinoids in cannabis go up in smoke.
In the fast-growing medical marijuana movement; individuals have developed many different methods of cannabis use. Of course, this phenomenon can also have positive and negative consequences. On a positive note, these products can exploit the therapeutic potential of the plant for many different diseases. On the other hand, these different consumption methods can lead to confusion in patients who have to experiment with different techniques to achieve optimal relief.
When most people think of cannabis, the first thought they think about is smoking, whether through blunts, joints, whistles or bongs. Although this is the most popular method of consumption, it is not the healthiest. When someone inhales cannabis, the majority of cannabinoids enter the body via the lungs, where they enter the bloodstream directly. Because of this direct exchange, the consumption of cannabis by inhalation has the shortest effect of all entry routes.
Additionally to smoking, cannabis can also be taken by vaping. Many products make this process easier, including portable vapes, stationary vaporizers, and even dabbing instruments. From a health perspective, many studies comparing the difference between smoking and vaporizing show significant benefits associated with vaporization, including more efficient cannabinoid extraction and reduced exposure to toxic elements such as carbon monoxide and tar derived from smoking.
Lovingly referred to as an infused edible product orally consumed cannabis enters the bloodstream after it has been digested or broken down in the stomach and absorbed in the gut. Usually, this is achieved by infusing butter or fatty oils with heat to produce a decarboxylated medicinal meal. Popular types of infused food on the shelves are brownies, candy, candy bars, biscuits, drinks, pills, snacks, spreads and more.
Patients who use cannabis orally usually report that they feel the effects within 30 minutes. The peak effects are around the 1-hour mark, and the total duration of the impact is up to 6 hours, although this depends on a variety of factors, including your tolerance level and the number of cannabinoids consumed, from which ratio of cannabinoids the edible is and more. The reason why edible substances work on you longer than smoking or vaporizing cannabis is due to the digestive process, where the edible matter has to be broken down from its original food state into a molecular cannabinoid state in order to be ingested.
The progressive nature of the digestion process explains the more prolonged effects for this type of consumption. It’s also important to note that factors such as the amount of food consumed before medication, the strength of the product and even a person’s metabolism can affect the overall experience.
Apart from the fact that cannabis is a vegetable with many of the same nutrients as other leafy vegetables (such as fibre, iron and calcium), it is packed with useful cannabinoids, which are unique to the cannabis plant. As such, juiced cannabis is a nutritionally dense, highly effective drug without the psychoactive ingredients typically found on heating the plant.
The high concentration of crude cannabinoic acids in juiced cannabis combined with perfectly balanced fatty acids; which could help improve cell function and reduce free radical damage. Additionally, the benefits of raw, juiced cannabis include reduced inflammation and facilitating bidirectional cellular communication. Many cannabinoids also have antitumor properties that are readily available by consuming raw marijuana.
However, like other vegetables, cannabis loses much of its nutritional value after heating. However, by juicing cannabis (rather than cooking or otherwise heating it), consumers can avoid high altogether without compromising its other valuable components. Because raw, juicy cannabis does not produce high levels, it is possible to consume much larger quantities of useful cannabinoids. For example, it has been shown that CBD inhibits or even reverses the growth of certain cancers, but only in extremely high doses.
Topic / Transdermal
Cannabinoids, like the drugs in other medicines, can also be absorbed through the skin. Products developed for this feature are referred to as cannabis topics. The skin has a pretty complicated absorption method that mainly involves how dissolvable a substance is in water. Examples of topical products are creams, balms and even patches, which are often used to quit smoking cigarettes.
Although not extensively studied, researchers have found that the topical application of cannabinoids takes place locally within minutes (i.e., creams and balms applied to a joint), with the duration of these effects being about one to two hours. A transdermal patch is a medical dressing that can be used to your skin to deliver cannabinoids to your system at a controlled release rate.
Although they are difficult to find in medical marijuana collectives these days, the transdermal patch has existed since 1979. People who used patches reported that the effect began within two hours and the duration of action was more than two days.
I would say that the best two ways to take Rick Simpson Oil, especially for when helping with situations like cancer is to take subliminally or juicing. If you are looking to take cannabis in the form of CBD for anxiety then I would recommend vaping as it is a quick and easy way to get it into your system.